02- CLINICAL DEVELOPMENT

Immunological Basis To AD Treatment

Think we’ve heard this story a thousand time before and every Global pharma Phase III trial has failed with it! I thought they’d realised that targeting AB protein had a basic flaw – that is that some people have amyloid plaques but no AD! >>>Immunological Target<<<

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Alzheimers ‘Brain’ Prize

Goedert, De Strooper, Hardy and Haas – leaders in neurological research! I like Hardy’s comment about current treatments being prescribed too late after the onset of the disease It’s unlikely we’ll find a revolutionary treatment but hopefully we’ll make small steps in to slowing the disease in the next few years <<BRAIN>>

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Shire New Drug Application

Not everything they do is aimed at rare disease <<<Constipation>>

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Novel Way To Boost Patient Recruitment

I’ve been waiting for something like this for sometime Gives the CRO/Phar,ma more control over patient recruitment Can’t be bad! >>> <<Recruitment>>>

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Hemostasis – Nanoparticles Of Thrombin

Interesting idea and maybe better than some of the devices we’ve been working on 🙂 Not sure I trust Russians though at the moment <<Hemostasis>>    

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Opioid Pain Killer Addiction

A hot topic with suboxone at the moment Not sure how Adapax (benzhydrocodone and acetaminophen) from Kempharm differentiates itself – especially as still ‘high potential for abuse’ Its just a combination of a couple of old drugs and ‘KemPharm hoping to differentiate its product once it hits the market’ sounds vague But basically its $150m […]

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AZ TO SPINOUT VIELA BIO

Six biologics to be fast tracked from MedImmune (AZ owned) through a separate company – Viela Bio Inflammatory and auto-immune (incl neuromyelitis) – all rare diseases They’ll make a fortune! All because outside AZ core >>> oncology, respiratory and cardiovascular and metabolic disease (seems pretty broad to me!)   J&J situation with Actelion buyout where […]

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Big Data At The NHS

Now this really could be huge Lifetime data from millions – a statisticians dream! Trouble is the brits have a reputation for giving away crown jewels – penicillin – jet engine – internet! John Bell is absolutely right! We need to make sure this doesn’t end up in California! <<BIG DATA>>>

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Diabetes Types

I didn’t know there were 5 – Type IIs Auto-immune / Insulin deficient / Insulin resistant / Obesity related / Age related With Obesity and Age making up 60%! <<Diabetes>>

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Thermostable Vaccines

Now this is a very simple idea and a very clever way of extending the use of vaccines No wonder Prokarium have the funding for Vaxonella <<<Vaccines>>>

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