02- CLINICAL DEVELOPMENT

NIH – Alzheimers Funding Increase

Big news announcement today NIH to get $414m for Alzheimer’s Research to take total to $1.8bn!!! <<<FUNDING>>>

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Mobile App to Monitor The Gut

Very interesting stuff and major potential for IBS maybe? <<<GUT MONITORING>>>

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Access To FDA NDA CSRs!!!

Wow – Access to full Pharma reports! <<<CSRs>>>

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Celgene Getting Into AD ‘Big Time’

Looks like Celgene are risking $100 upfront to partner with Prothena’s (Irish Biotech) Tau antibody programme Tau targets are the latest alternative to amyloid They are however ‘edging their bets’ by also putting $100 into Vividion programme to develop new small molecule treatments <<<Celgene>>>

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Health care — especially for seniors — is at its breaking point and is ripe for disruption

Is this why Amazon are getting involved? 🙂 <<<Amazon>>>

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Precordia: Abnormal ECG App To Detect

Precordia company from Turku University have come up with great idea Using accelerometers in smartphones to detect abnormal heart rhythms Then analysing it to predict stroke. blood clots and heart failure <<<ECG>>>

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Male Contraceptive: dimethandrolone

Do you really want to be messing with vital hormones!!! Testosterone lowering is not a good idea in my book They have no idea of the long term effects or what else they potentially impair like growth and cell repair   <<<TESTOSTERONE>>>

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UK Increasing Mortality Rate

Interestingly they reckon not due to ageing, flu or cold weather but might be up turn in cancelled operations Would be an interesting modelling project 🙂   <<<MORTALITY>>>

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Toxic Nerve Agents

All very topical given the last weekends activities in our little own hometown – Salisbury! Looks like these nerve toxins like Sarin and Vx are just pumped up versions of the Acetylcholine esterase inhibitors we use for Alzheimers! They like our old friend galantamine (we did all the early development work) just block the breakdown […]

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The ‘Amazon’ Approach To Clinical Trial Recruitment

Nicely put – rather have the patient ‘shop’ at the clinic take the ‘shop’ on line to the patient 🙂 Ok if the condition your treating allows for home assessment and you can validate ‘real life’ data But always useful for follow ups <<<AMAZON>>>

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