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Red Bull As Symptomatic Treatment In AD?

Keith’s CogTrack finds some interesting effects on short/long term memory and speed of retrieval >>> Study: Red Bull energy drink boosts memory performance

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Yet Another Failure In AD

This time Merck’s BACE inhibitor of amyloid beta >> http://www.pharmatimes.com/news/merck_pulls_plug_on_late-stage_alzheimers_trial_1186737?utm_source=PT+Daily+Newsletter&utm_medium=email&utm_campaign=pt+daily+news+alert

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Another Phase III Trial In AD Going ‘Gungho’!

Apparently 11 patients treated is sufficient now for developers to go straight into a big Phase III trials Sounds like Lilly all over again! Whatever happened to classic drug development? Obviously the review article I did with Bengt Winblad and Julian Gray didn’t put any one off >> http://www.fiercebiotech.com/biotech/early-win-means-phase-3-test-way-for-axovant-s-dementia-drug?utm_medium=nl&utm_source=internal&mrkid=938224&mkt_tok=eyJpIjoiTTJRNE1UQTNNV1prWVdRMCIsInQiOiI3UlpZdEFXMTRldkIySSt3WFQyaitKVGl2YkNENWRNY0V1eUtESjJ5ellmQVVmaURvWXNIbmppYmxjSmZUczA3TkwxejRZMnpvSmlXdTExZk1aYUFIWG1JM1RTT0d4ZGpaR0dGckVybVdMQTgrWDc0VFdBN0ZcLzdrcllkSlh3UjgifQ%3D%3D

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Financial Analysts Try to Be Statisticians in NASH Trial!!!

Very interesting new press release No idea why the Intercept share price went down given that it’ll be much easier now to get a positive trial result with statistical significance on only one or other of the co-primary endpoints and it’s reduced the number of subjects required in total as well! It certainly does raise […]

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Lab On A Chip Future

Fascinating stuff from Stanford using electrophoresis in a microfluidic chamber to diagnose diseases And affordable >>> http://newatlas.com/stanford-microfluidic-lab-on-a-chip/47775/?utm_source=Gizmag+Subscribers&utm_campaign=a8bafb40ef-UA-2235360-4&utm_medium=email&utm_term=0_65b67362bd-a8bafb40ef-91677545

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Yet Another Failure In AD!!!

Lundbeck’s 5-HT6 antafonist (idalopirdine ) has failed in 3 attempts >>> http://www.fiercebiotech.com/biotech/lundbeck-calls-time-alzheimer-s-drug-after-more-failure?utm_medium=nl&utm_source=internal&mrkid=938224&mkt_tok=eyJpIjoiTkdNNU1UZGxNR05pTjJJeiIsInQiOiJxWnhDQTcySXZCQm1MeTE4THZXWEVnTlZGa1JNMVRVOVNmVFFCUHZTWjJrZkRBdjJPY2Zxd0l0aVdOOEZaMVwvWFdSNUI0dlNaaFArWWd2eVNNUGJndllOVDZKdjZ2ZUREdmQyWDIzcTdmOFRtMHpuYmp1QUpSYUxObU9mSmo2NXQifQ%3D%3D

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Is This The Holy Grail?

Bioelectric systems Sensing the environment and triggering response through electrochemical response Disease/Illness detection and treatment ‘all in one’!!! >>>> http://newatlas.com/cyborg-technology-scientists-create-bioelectric-hybrid-cells/47481/?utm_source=Gizmag+Subscribers&utm_campaign=69a7338016-UA-2235360-4&utm_medium=email&utm_term=0_65b67362bd-69a7338016-91677545

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War On AD?

News items in the Times over the last 2 days. Seems like the disease is still winning for all our efforts >>> http://www.thetimes.co.uk/past-six-days/2017-01-30/news/drug-failure-deals-blow-to-dementia-sufferers-ll27jd65r http://www.thetimes.co.uk/edition/news/century-long-war-on-alzheimers-edges-towards-uncertain-endgame-n9mm9k0jk

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Does This Mean There’ll Be Competition For LSD In Dementia In Future?

The benefits of microdosing LSD, although cognition wasn’t specifically mentioned>>>> http://newatlas.com/lsd-long-trip/47551/?utm_source=Gizmag+Subscribers&utm_campaign=2a58092796-UA-2235360-4&utm_medium=email&utm_term=0_65b67362bd-2a58092796-91677545

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More Clinical Trials In AD News

Another Phase II with an Anit-Tau antibody (AbbVie) Does this bode well for the ‘front runner’ Axon especially after TauRx fell at the first? And what about the others in the pack at the back: Eisai/Biogen, Bristol-Myers Squibb and Astellas? >>>> eyJpIjoiWWprNU56UmhPR1ppT1RFeCIsInQiOiJxTTlsOWcxaWZkU3YwVmF2TFFYOUhNTVg1eDJpTVVPWGRVUGN4cXdFSjlLMzcyM2J6Tld0OWc2OEpjekE2MGdBeVJORmFWelZ5Sk5yNkdadSs1VkhKajMwYjRBSGthdHlFbHVFRGh6UWo5aHdyNjJLclY1NnpPb0RlQ25GWjdVRCJ9  

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