AI To Be Used To identify Chronic Diseases Earlier – Theresa Says
Really!!! Have they any idea of implications for NHS – can they cope with the rush for treatment <<<AI>>
Really!!! Have they any idea of implications for NHS – can they cope with the rush for treatment <<<AI>>
Fairly logical really but certainly a 40,000 patient study would give weight to the conclusions!!! Also adds weight to the use of AChEs for the symptomatic relief of cognitive symptoms in confirmed AD patients <<<AntiCholinergics>>>
HoL picked up on basic deficiency in this strategy then Give it to the NHS but don’t tell them 🙂 <<<NHS>>>
Interesting article from Cytel Fairly obvious really – Some really simple rules! -Only select few really good sites (50% don’t recruit) -Don’t make protocol too extensive and complicated (don’t want amendments) -Collect only essential info not nice to have -Don’t do adaptive designs! <<Part 1>> <<Part 2>>
For too long AD have been a too highly variable environment for clinical research! -The patients present with highly variable conditions -The treatments have widely different modes of action and possible targets -The assessment measures are highly variable and subject to large errors No wonder it has been almost impossible to pick up any indicators […]
Subjects with 2 ApoE4 genes are 12 times more likely to get AD than those with the normal gene (ApoE3) So although scientists know that amyloid protein breakdown is important in the disease therapeutics targetting these proteins has been one long list of failures This is a very interesting potential explanation – neurons produced from […]
First it was Lilly then Pfizer then Axovant then Merck and almost Biogen/Eisai and now vTV (whoever they are) But then it was only 2 lots of 400 patients and the ADAS and CDR – what did they expect! <<<ALZ>>>
Very interesting stuff from Pharma Times Distributed security applied to patient health records right through to drug supply <<<BLOCKCHAIN>>>
Doesn’t look like Statisticians will be running out of things to do any time soon 🙂 <<<REAL WORLD>>>
I’m sure we did some sample size calcs for Michalis sometime ago <<<BRAINOMIX>>